Ruud P M Dings Selected Research

compound 0118

12/2017	Galectin-1 Inhibitor OTX008 Induces Tumor Vessel Normalization and Tumor Growth Inhibition in Human Head and Neck Squamous Cell Carcinoma Models.
6/2012	Antitumor agent calixarene 0118 targets human galectin-1 as an allosteric inhibitor of carbohydrate binding.
7/2008	Ovarian tumor growth regression using a combination of vascular targeting agents anginex or topomimetic 0118 and the chemotherapeutic irofulven.

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Ruud P M Dings Research Topics

Disease

47	Neoplasms (Cancer) 01/2021 - 12/2002
5	Breast Neoplasms (Breast Cancer) 12/2020 - 09/2008
5	Hypoxia (Hypoxemia) 11/2018 - 06/2007
5	Carcinoma (Carcinomatosis) 11/2015 - 10/2004
4	Neoplasm Metastasis (Metastasis) 07/2018 - 04/2007
3	Communicable Diseases (Infectious Diseases) 06/2013 - 10/2007
2	Squamous Cell Carcinoma of Head and Neck 01/2021 - 12/2017
2	Melanoma (Melanoma, Malignant) 01/2021 - 12/2019
2	Dysbiosis 01/2021 - 12/2019
2	Lung Neoplasms (Lung Cancer) 11/2018 - 01/2017
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 12/2017 - 11/2015
2	Ovarian Neoplasms (Ovarian Cancer) 04/2007 - 06/2004
1	Infections 12/2019
1	Lewis Lung Carcinoma 12/2019
1	Glioma (Gliomas) 07/2018
1	Glioblastoma (Glioblastoma Multiforme) 07/2018
1	Circulating Neoplastic Cells 10/2017
1	Triple Negative Breast Neoplasms 01/2017
1	Bacteremia 06/2013
1	Type 2 Diabetes Mellitus (MODY) 01/2012
1	Fibrosarcoma 01/2012
1	Hyperthermia 01/2010
1	Body Weight (Weight, Body) 09/2008

Drug/Important Bio-Agent (IBA)

10	Angiogenesis InhibitorsIBA 06/2012 - 01/2003
8	Pharmaceutical PreparationsIBA 01/2021 - 06/2004
7	Galectin 1 (LGALS1)IBA 01/2019 - 10/2006
7	Peptides (Polypeptides)IBA 10/2013 - 11/2003
5	Proteins (Proteins, Gene)FDA Link 01/2021 - 08/2005
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 07/2018 - 06/2004
3	Anti-Bacterial Agents (Antibiotics)IBA 01/2021 - 06/2013
3	compound 0118IBA 12/2017 - 07/2008
3	Oxygen (Dioxygen)IBA 12/2017 - 02/2007
3	AngiostatinsIBA 04/2006 - 01/2003
2	Membrane Proteins (Integral Membrane Proteins)IBA 01/2021 - 07/2006
2	Hemoglobins (Hemoglobin)IBA 01/2021 - 08/2018
2	CytokinesIBA 12/2019 - 12/2006
2	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 12/2019 - 11/2006
2	Biological ProductsIBA 03/2018 - 10/2017
2	Bevacizumab (Avastin)FDA Link 12/2017 - 06/2007
2	pimonidazoleIBA 12/2017 - 01/2015
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2017 - 11/2015
2	AntigensIBA 01/2017 - 01/2015
2	Calixarenes (Calixarene)IBA 01/2015 - 10/2013
2	Cytotoxins (Cytolysins)IBA 10/2013 - 01/2010
2	calix(4)areneIBA 10/2013 - 06/2012
2	Angiogenic ProteinsIBA 06/2012 - 12/2002
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 06/2007 - 11/2006
2	EndostatinsIBA 04/2007 - 04/2006
2	Carboplatin (JM8)FDA LinkGeneric 06/2004 - 01/2003
1	GSK 1363089IBA 01/2021
1	Biomarkers (Surrogate Marker)IBA 01/2021
1	AntibodiesIBA 12/2020
1	Immune Checkpoint InhibitorsIBA 12/2020
1	Lymphocyte Function-Associated Antigen-1 (LFA-1)IBA 12/2019
1	CollagenIBA 01/2019
1	CB-839IBA 01/2019
1	GlutaminaseIBA 01/2019
1	Glutamine (L-Glutamine)FDA Link 01/2019
1	Glutathione (Reduced Glutathione)IBA 01/2019
1	antineoplaston A10 (A 10)IBA 01/2019
1	LipidsIBA 01/2019
1	Glucose (Dextrose)FDA LinkGeneric 11/2018
1	Protein-Lysine 6-Oxidase (Lysyl Oxidase)IBA 07/2018
1	PotassiumIBA 07/2018
1	DisintegrinsIBA 07/2018
1	ThrombospondinsIBA 07/2018
1	Small Nucleolar RNA (snoRNA)IBA 07/2018
1	ProteomeIBA 07/2018
1	Metalloproteases (Metalloproteinases)IBA 07/2018
1	Galectins (Galectin)IBA 03/2018
1	Flavin-Adenine Dinucleotide (FAD)IBA 01/2017
1	Estrogens (Estrogen)FDA Link 01/2017
1	NAD (NADH)IBA 01/2017
1	Progesterone FDA LinkGeneric 01/2017
1	Epithelial Cell Adhesion MoleculeIBA 01/2017
1	PlatinumIBA 01/2017
1	taxaneIBA 01/2017
1	GoldIBA 11/2015
1	CYT-6091IBA 11/2015
1	Tazobactam Drug Combination Piperacillin (Zosyn)FDA LinkGeneric 06/2013
1	Cell Surface ReceptorsIBA 03/2013
1	Metformin (Glucophage)FDA LinkGeneric 01/2012
1	acylfulveneIBA 01/2010
1	CarcinogensIBA 09/2008
1	LignansIBA 09/2008
1	Estrogen Receptor betaIBA 09/2008
1	lariciresinolIBA 09/2008
1	anthraceneIBA 09/2008
1	Hormones (Hormone)IBA 09/2008
1	irofulvenIBA 07/2008
1	Semaxinib (SU5416)IBA 04/2007

Therapy/Procedure

18	Therapeutics 01/2021 - 06/2004
14	Radiotherapy 01/2021 - 06/2005
3	Immunotherapy 12/2020 - 04/2006
2	Aftercare (After-Treatment) 11/2018 - 08/2018
2	Injections 06/2005 - 05/2003
1	Optical Fibers 01/2021
1	Lasers (Laser) 01/2019
1	Precision Medicine 01/2017
1	Microbubbles 01/2015